The Science Behind Restore
Evidence based nutritional support formulated specifically for adults on GLP-1 therapy. Every ingredient, every dose, backed by research.
GLP-1 Medications Work. But Side Effects Are Real.
Nausea, fatigue, and digestive discomfort cause thousands to stop therapy before reaching their health goals.
GLP-1 receptor agonist like semaglutide (Ozempic, Wegovy) and tirzepatide (Mounjaro, Zepbound) have transformed weight management and metabolic health. These medications work by mimicking hormones that reduce appetite and slow digestion–helping millions achieve their health goals.
But there’s a challenge. In a 2025 meta analysis of clinical trials, researchers found that gastrointestinal side effects affect the majority of GLP-1 users.
The symptoms are most intense during the first weeks of therapy and after dose increases. While many patients report that side effect diminish over time, the discomfort can be significant enough that approximately 1-in-3 patients discontinue therapy within the first six months.
That’s why we founded novi. Patients need more than just medication. They need comprehensive nutritional support to stay comfortable, stay consistent, and achieve their health goals.
Pharmacist Led. Evidence Based. Patient Focused.
We need a new sub headline here
Our products aren’t created in marketing meetings. We create products for ourselves–products that we use every day.
Restore was formulated by a team member with first hand experience managing the side effects from GLP-1 therapy. The nausea, headaches, upset stomach and low energy.
Each ingredient in Restore was thoroughly researched and vetted to ensure that it provided critical nutrients to help manage the nutritional gap while on GLP-1 therapy.
Our Formulation Philosophy
Three principles guide every ingredient decision: target root causes, follow the science, and maintain uncompromising quality standards.
Target Root Causes, Not Just Symptoms
We don’t just throw popular supplements together. Each ingredient is selected to address the specific physiological mechanisms behind GLP-1 side effects:
Hydration support for headaches and dizziness (electrolytes)
Digestive regulation for nausea and GI distress (ginger, probiotics, fiber)
Energy metabolism for fatigue (B-vitamin complex)
Nutritional insurance for reduced food intake (superfoods, minerals)
Evidence Based Ingredient Selection
Every ingredient in novi Restore is supported by peer-reviewed research. We prioritized:
Clinical studies demonstrating efficacy for specific symptoms.
Established safety profiles with minimal drug interactions.
Bioavailable forms (like methylcobalamin B12, not cyanocobalamin)
Appropriate therapeutic doses
cGMP Manufacturing Standards
Our products are manufactured in the USA by an FDA registered, cGMP certified facility. This means:
Rigorous quality control at every production stage
Third party testing for purity and potency
Batch traceability
Compliance with FDA dietary supplement regulations
Manufactured to the Highest Standards
Quality isn’t negotiable when it comes to supplements. That’s why Restore is products in an FDA registered, cGMP certified facility with rigorous quality control at every step.
How it Works
Three principles guide every ingredient decision: target root causes, follow the science, and maintain uncompromising quality standards.
Tips for Optimal Results
Start Early
Begin taking Restore 2–3 days before your first GLP-1 dose to establish baseline hydration & nutrition levels.
Take Daily
Consistency matters–benefits build over time, especially for gut health.
Timing Flexibility
Take with breakfast or 30 minutes before your GLP-1 injection to preemptively manage nausea.
Pair with Food
Mix with 12 oz of water and consume alongside a small meal for better absorption.
Stay Hydrated
novi promotes hydration but isn’t a replacement–continue drinking water throughout the day.
What's Inside Restore
novi Restore contains sight key ingredients specifically chosen to support your GLP-1 journey:
Organic Ginger Root
Supports digestive calm and helps ease nausea naturally, a trusted remedy used for centuries for stomach ache.
Organic Reds Blend
Delivers twelve antioxidant-rich superfoods to provide phytonutrients and support overall wellness.
Electrolyte Blend
Promotes balanced hydration and helps reduce dizziness and headaches when appetite and fluid intake are low.
Green Tea Extract
Bioavailable antioxidants promote digestive calm and metabolic wellness.
Probiotic Blend
Helps maintain gut regularity and support healthy digestion as your body adjusts to therapy.
Ginko Biloba Leaf
Provides additional antioxidant support with flavonoids and terpenoids.
B-Vitamin Complex
Supports natural energy production, mental clarity, and help combat fatigue during weight loss.
Essential Minerals
Supports metabolic processes, thyroid function, and overall wellness during therapy.
Grounded in Peer-Reviewed Science
Explore the research behind he hydration, digestion, and nutrient pathways that support adults on GLP-1 therapy.
Built on decades of nutritional research, each ingredient in novi Restore was selected because it has been stufied for its role in hydration, digestion, energy metabolism, and overall wellness. We don’t rely on trends or guesswork–our clinical pharmacist reviews the evidence behind every component before it makes it way into the formula.
This section highlights peer-reviewed studies supporting the physiological functions behind our ingredients. While the research is ongoing, the existing body of evidence helps explain why supporting hydration, gut balance, and micronutrient intake can make a meaningful difference for adults managing GLP-1 therapy.
We’ve included source materials below so you can explore the science for yourself. Curiosity welcomed.
Research demonstrates that adequate hydration and electrolyte balance are essential for preventing dehydration headaches and supporting overall physiological function.
Study: "Water, Hydration, and Health" -
Nutrition Reviews
Fourteen randomized trials demonstrate that ginger significantly reduces nausea, vomiting, and the need for antiemetic drugs across various clinical populations.
Study 1: "Efficacy of Ginger for Prophylaxis of Chemotherapy-Induced Nausea and Vomiting" - Nutrients
Multiple randomized controlled trials collectively favor ginger over placebo for reducing nausea and vomiting symptoms
Study 2: "A Systematic Review of Randomized Controlled Trials of Ginger for Nausea and Vomiting"
Probiotics have been shown to positively influence gut transit time, bowel movement frequency, and overall digestive comfort in clinical studies.
Study 1: "Effects of Probiotics on Gastrointestinal Function" - BMC Gastroenterology
Combined prebiotic and probiotic supplementation supports beneficial gut bacteria, promotes digestive regularity, and enhances intestinal barrier function.
Study 2: "Prebiotics and Probiotics: Health Benefits and Mechanisms"
B vitamins are essential for energy metabolism and cellular function, with deficiencies potentially impairing cognitive performance and contributing to fatigue.
Study: "B Vitamins and the Brain: Mechanisms, Dose and Efficacy" - Nutrients
Green tea compounds support metabolic health and may promote digestive comfort by reducing gut inflammation and modulating intestinal function.
Study: "Green Tea Catechins and Their Role in Metabolic Health and Gut Function"
Ready to Feel Your Best?
Consistency is everything when it comes to reaching your health goals. Start your wellness routine today.
